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Research

Current Publications

2024 Publications

Goldenberg, J. Z., Batson, R. D, Pugh, M. J., Zwickey, H, Beardsley, J., Zeegers, M. P., & Freeman, M. The Cumulative Incidence of Post-Traumatic Epilepsy After Mild Traumatic Brain Injury: A Systematic Review and Individual Participant Data Meta-Analysis Protocol. Neurotrauma Reports 2024;5 (1): 522–28.

Wexler RS, Fox DJ, ZuZero D, et al. Virtually delivered Mindfulness-Oriented Recovery Enhancement (MORE) reduces daily pain intensity in patients with lumbosacral radiculopathy: a randomized controlled trial. Pain Rep. 2024;9(2):e1132. Published 2024 Mar 14. doi:10.1097/PR9.0000000000001132

Vita, A. A., Roberts, K. M., Gundersen, A., Farris, Y., Zwickey, H., Bradley, R., & Weir, T. L. (2024). Relationships between Habitual Polyphenol Consumption and Gut Microbiota in the INCLD Health Cohort. Nutrients16(6), 773. https://doi.org/10.3390/nu16060773 

Jamieson PE, Smart EB, Bouranis JA, Choi J, Danczak RE, Wong CP, Paraiso IL, Maier CS, Ho E, Sharpton TJ, Metz TO, Bradley R, Stevens JF. Gut enterotype-dependent modulation of gut microbiota and their metabolism in response to xanthohumol supplementation in healthy adults. Gut Microbes. 2024 Jan-Dec;16(1):2315633. doi: 10.1080/19490976.2024.2315633. Epub 2024 Feb 15. PMID: 38358253; PMCID: PMC10878022.

Leyde S, Price CJ, Colgan DD, Pike KC, Tsui JI, Merrill JO. Mental Health Distress Is Associated With Higher Pain Interference in Patients With Opioid Use Disorder Stabilized on Buprenorphine or Methadone. Subst Use Addctn J. 2024 Feb 7:29767342241227402. doi: 10.1177/29767342241227402. Epub ahead of print. PMID: 38327009.

Ridda I, Rafiq S, Rashid H, Koul PA, . Innovative Approaches in Continuing Medical Education: Revolutionizing the Path to Excellence. J Pub Health Comm Med. 2024; 1(2): 1-10. doi:10.5455/JPHCM.20240124073537

Tichauer C, Corroon J, Fain R, Erlandsen A, Bradley R. High Dose Intravenous Vitamin C for Lyme Disease: A Safety and Tolerability Study with an Exploratory Assessment of Treatment Efficacy. Medical Research Archives, [S.l.], v. 12, n. 1, Jan. 2024. ISSN 2375-1924.


2023 Publications

Investigators at Helfgott Research Institute conducted numerous studies and published 26 peer-reviewed papers in 2023, providing continued high quality research in the field of integrative health. Below are the details of each 2023 study and links to the published work.

Sharpe E, Butler MP, Clark-Stone J, Soltanzadeh R, Jindal R, Hanes D, Bradley R. A closer look at yoga nidra- early randomized sleep lab investigations. J Psychosom Res. 2023 Mar;166:111169. doi: 10.1016/j.jpsychores.2023.111169. Epub 2023 Jan 29. PMID: 36731199; PMCID: PMC9973252.

Alshahrani, N.Z.; Ridda, I.; Rashid, H.; Alzahrani, F.; Othman, L.M.B.; Alzaydani, H.A. Willingness of Saudi Adults to Receive a COVID-19 Vaccine Booster Dose. Sustainability 2023, 15, 920. doi: 10.3390/su15020920

Fox DJ, Hanes D. Prevalence and Correlates of Unmet Mental Health Services Need in Adolescents With Major Depressive Episode in 2019: An Analysis of National Survey on Drug Use and Health Data. J Adolesc Health. 2023 Feb;72(2):182-188. doi: 10.1016/j.jadohealth.2022.10.001. Epub 2022 Nov 22. PMID: 36424335.

Buttolph L, Wooliscroft L, Bradley R, Zwickey H. Participant Perspectives on Community Qigong for People with Multiple Sclerosis. Integr Med Rep. 2023 Feb 1;2(1):26-34. doi: 10.1089/imr.2022.0079. Epub 2023 Feb 1. PMID: 36895618; PMCID: PMC9986858.

Bray B, Sadowski A, Bray C, Bradley R, Zwickey H. Clinical aspects of binge eating disorder: A cross-sectional mixed-methods study of binge eating disorder experts’ perspectives. Front Psychiatry. 2023 Feb 14;13:1087165. doi: 10.3389/fpsyt.2022.1087165. PMID: 36864846; PMCID: PMC9971930.

Boutros SW, Zimmerman B, Nagy SC, Unni VK, Raber J. Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and baseline DNA damage in the hippocampus. Mol Psychiatry. 2023 Feb 2. doi: 10.1038/s41380-023-01966-8. Epub ahead of print. PMID: 36732588.

Karam G, Agarwal A, Sadeghirad B, Jalink M, Hitchcock CL, Ge L, Kiflen R, Ahmed W, Zea AM, Milenkovic J, Chedrawe MA, Rabassa M, El Dib R, Goldenberg JZ, Guyatt GH, Boyce E, Johnston BC. Comparison of seven popular structured dietary programmes and risk of mortality and major cardiovascular events in patients at increased cardiovascular risk: systematic review and network meta-analysis. BMJ. 2023 Mar 29;380:e072003. doi: 10.1136/bmj-2022-072003. PMID: 36990505; PMCID: PMC10053756.

Bruton AM, Senders A, Tost G, Ast H, Robinette LM, Leung B, Hatsu IE, Arnold LE, Johnstone JM. Pain sensitivity and perceptual sensitivity are associated with severity of emotional dysregulation in children with ADHD: a cross-sectional analysis using the Temperament in Middle Childhood Questionnaire. Disabil Rehabil. 2023 Mar;45(5):848-856. doi: 10.1080/09638288.2022.2043946. Epub 2022 Mar 10. PMID: 35271401; PMCID: PMC9463405.

Robinette LM, Hatsu IE, Johnstone JM, Bruton AM, Leung BMY, Arnold LE. Treatment response to supplemental nutrients for ADHD is independent of diet quality: the MADDY Study RCT. Nutr Neurosci. 2023 Mar 29:1-10. doi: 10.1080/1028415X.2023.2191415. Epub ahead of print. PMID: 36989335.

Kaplan J, Colgan DD, Klee D, Hanes D, Oken BS. Patterns of Respiration Rate Reactivity in Response to a Cognitive Stressor Associate With Self-Reported Mental Health Outcomes. Psychol Rep. 2023 Apr 21:332941231171887. doi: 10.1177/00332941231171887. Epub ahead of print. PMID: 37083201. 

Wexler RS, Norcross C, Fuller L. Challenging Case in Clinical Practice: Multimodal Management of Concurrent Structural and Virally Exacerbated Trigeminal Neuralgia. Integrative and Complementary Therapies. 2023 April;29(2):67-71. https://doi.org/10.1089/ict.2023.29069.rsw

Nunez J, Corroon J, Vilke G, Castillo E, Alfaraj DN, Coyne CJ. Perceptions and Practices of Cannabis Use Among Emergency Department Patients. J Emerg Med. 2023 May;64(5):543-554. doi: 10.1016/j.jemermed.2023.02.003. Epub 2023 Mar 21. PMID: 37032203.

Zare H, Amiri Ardekani E, Tavakoli A, Bradley R, Tavakoli F, Pasalar M. Reporting of adverse effects of pomegranate in clinical studies: a systematic review. J Complement Integr Med. 2023 May 1. doi: 10.1515/jcim-2022-0247. Epub ahead of print. PMID: 37116077.

Simmons A, Vasquez A, Green K, Christopher M, Colgan DD. The impact of ethnic discrimination on chronic pain: the role of sex and depression. Ethn Health. 2023 May 3:1-16. doi: 10.1080/13557858.2023.2208315. Epub ahead of print. PMID: 37137819.

Robinette LM, Hatsu IE, Johnstone JM, Tost G, Bruton AM, Leung BMY, Odei JB, Orchard T, Gracious BL, Arnold LE. Fruit and vegetable intake is inversely associated with severity of inattention in a pediatric population with ADHD symptoms: the MADDY Study. Nutr Neurosci. 2023 Jun;26(6):572-581. doi: 10.1080/1028415X.2022.2071805. Epub 2022 May 10. PMID: 35535573; PMCID: PMC9646924.

Leung BMY, Srikanth P, Robinette L, Bruton AM, Tost G, Hatsu I, Arnold LE, Johnstone JM. Micronutrients for ADHD in youth (MADDY) study: comparison of results from RCT and open label extension. Eur Child Adolesc Psychiatry. 2023 Jun 8. doi: 10.1007/s00787-023-02236-2. Epub ahead of print. PMID: 37291464.

Sandison H, Callan NGL, Rao RV, Phipps J, Bradley R. Observed Improvement in Cognition During a Personalized Lifestyle Intervention in People with Cognitive Decline.  J Alzheimers Dis. 2023 Jun 19. doi: 10.3233/JAD-230004. Epub ahead of print. PMID: 37355891.

Wexler RS, Fuller L. Intravenous Magnesium Sulfate Reduces Tremor Severity: A Case Series. Altern Ther Health Med. 2023 Jul;29(5):82-85. PMID: 37295004.

Bowie, D.C., Low, K.A., Rubenstein, S.L., Islam, S.S., Zimmerman, B., Sutton, B.P., Gratton, G., Fabiani, M. (2023).Neurovascular mechanisms of cognitive aging: arteriosclerosis precipitates demyelination and cognitive decline. Bioarxiv (submitted to Neurobiology of Aging).

Knorr AL, Wexler RS, Fuller L. Treatment of Epstein-Barr Induced Hepatitis with High Dose Intravenous Vitamin C: A Case Report. Integr Med (Encinitas). 2023 Sep;22(4):24-27. PMID: 37752927; PMCID: PMC10519236.

Quinn AM. Complex Presentations, Identification and Treatment of Mast Cell Activation Syndrome and Associated Conditions: A Case Report. Integr Med (Encinitas). 2023 Sep;22(4):36-41. PMID: 37752934; PMCID: PMC10519234.

Talukdar JR, Steen JP, Goldenberg JZ, Zhang Q, Vernooij RWM, Ge L, Zeraatkar D, Bała MM, Ball GDC, Thabane L, Johnston BC. Saturated fat, the estimated absolute risk and certainty of risk for mortality and major cancer and cardiometabolic outcomes: an overview of systematic reviews. Syst Rev. 2023 Sep 30;12(1):179. doi: 10.1186/s13643-023-02312-3. PMID: 37777760; PMCID: PMC10541715.

Guedry SE, Langley BO, Schaefer K, Hanes DA. Patient experience of chronic illness care and complementary integrative health use: a cross-sectional study of patients with hypermobility spectrum disorders (HSD) and Ehlers-Danlos syndromes (EDS). Disabil Rehabil. 2023 Oct;45(21):3549-3559. doi: 10.1080/09638288.2022.2131003. Epub 2022 Oct 12. PMID: 36222285.

Corroon J, Grant I, Allison MA, Bradley R. Associations Between Monthly Cannabis Use and Myocardial Infarction in Middle-Aged Adults: NHANES 2009 to 2018. Am J Cardiol. 2023 Oct 1;204:226-233. doi: 10.1016/j.amjcard.2023.07.065. Epub 2023 Aug 7. PMID: 37556891.

Webber LC, Anderson LN, Paraiso IL, Metz TO, Bradley R, Stevens JF, Wright AT. Affinity- and activity-based probes synthesized from structurally diverse hops-derived xanthohumol flavonoids reveal highly varied protein profiling in Escherichia coli. RSC Adv. 2023 Oct 11;13(42):29324-29331. doi: 10.1039/d3ra05296f. PMID: 37829707; PMCID: PMC10565736.

Corroon J, Grant I, Bradley R, Allison MA. Trends in Cannabis Use, Blood Pressure, and Hypertension in Middle-Aged Adults: Findings From NHANES, 2009-2018. Am J Hypertens. 2023 Nov 15;36(12):651-659. doi: 10.1093/ajh/hpad068. PMID: 37479221; PMCID: PMC10647009.

Other Past Publications