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Current Publications

Investigators at Helfgott Research Institute conducted numerous studies and published 34 peer-reviewed papers in 2021, providing continued high quality research in the field of integrative health. Below are the details of each 2021 study and links to the published work.

Alterations In Heart Rate Variability Associated With Irritable Bowel Syndrome Or Inflammatory Bowel Disease: A Systematic Review And Meta-Analysis.
Sadowski, A; Dunlap, C; Lacombe, A; Hanes, D. 
Published Jan. 2021
Clinical and Translational Gastroenterology 

Inflammatory Bowel Disease And Neutrophil–Lymphocyte Ratio: A Systematic Scoping Review.
Langley, B; Guedry, S; Goldenberg, J; Hanes, D; Beardsley, J; Ryan, J. 
Published Sept. 2021
Journal of Clinical Medicine.

Impact Of 2′-Fucosyllactose On Gut Microbiota Composition In Adults With Chronic Gastrointestinal Conditions: Batch Culture Fermentation Model And Pilot Clinical Trial Findings.
Ryan, J; Monteagudo-Mera, A; Contractor, N; Gibson, G. . 
Published Mar. 2021

Short-Term Tolerability, Safety, And Gut Microbial Composition Responses To A Multi-Strain Probiotic Supplement: An Open-Label Study In Healthy Adults.
Ryan, J; Patno, N. 
Published Feb. 2021. 
Integrative Medicine (Encinitas) 

The Effect Of Qigong Meditation On Serum Cortisol, BDNF, And Cognitive Function: A Pilot Study.
Whitney, T; Langley, B; Gonzalez, N; Hanes, D; Zwickey, H. 
Published July 2021
Journal of Restorative Medicine

Xanthohumol Microbiome And Signature In Healthy Adults (The Xmas Trial): Safety And Tolerability Results Of A Phase I Triple-Masked, Placebo-Controlled Clinical Trial.
Langley, B; Ryan, J; Hanes, D; Phipps, J; Stack, E; Metz, T; Stevens, J; Bradley, R. 
Published Apr. 2021
Molecular Nutrition & Food Research

Overeaters Anonymous: An Overlooked Intervention For Binge Eating Disorder.
Bray, B; Rodríguez-Martín, B; Wiss, D; Bray, C; Zwickey, H. 
Published July 2021
International Journal of Environmental Research and Public Health

Low And Very Low Carbohydrate Diets For Diabetes Remission.
Goldenberg, J; Johnston, B. 
Published May 2021. 

Efficacy And Safety Of Low And Very Low Carbohydrate Diets For Type 2 Diabetes Remission: Systematic Review And Meta-Analysis Of Published And Unpublished Randomized Trial Data.
Goldenberg, J; Day, A; Brinkworth, G; Sato, J; Yamada, S; Jönsson, T; Beardsley, J; Johnson, J; Thabane, L; Johnston, B. 
Published Jan. 2021 

Zinc For The Prevention Or Treatment Of Acute Viral Respiratory Tract Infections In Adults: A Rapid Systematic Review And Meta-Analysis Of Randomised Controlled Trials.
Hunter, J; Arentz, S; Goldenberg, J; Yang, G; Beardsley, J; Myers, S; Mertz, D; Leeder, S. Published Nov. 2021

Honeybee Products For The Treatment And Recovery From Viral Respiratory Infections Including SARS-COV-2: A Rapid Systematic Review.
Arentz, S; Hunter, J; Khamba, B; Mravunac, M; Lee, Z; Alexander, K; Lauche, R; Goldenberg, J; Myers, S. 
Published  Oct. 2021 
Integrative Medicine Research

Program Evaluation Of Trauma-Informed Yoga For Vulnerable Populations.
Tibbitts, D; Aicher, S; Sugg, J; Handloser, K; Eisman, L; Booth, L; Bradley, R. 
Published Oct. 2021
Evaluation and Program Planning

Effects Of Hydrastis Canadensis, Commiphora Habessinica, Phytolacca Americana, And Echinacea Purpurea On Bacterial Growth.
Corn, Joshua; Tibbitts, Deanne; Ito, Haruka; Schafer, Morgan; Vasilevsky, Nicole. 
Published Jul. 2021
Alternative Therapies in Health and Medicine

A Closer Look At Yoga Nidra: Sleep Lab Protocol.
Sharpe, Erica; Lacombe, A; Butler, M; Hanes, D; Bradley, R. 
Published Jan. 2021
International Journal of Yoga Therapy 

Comparison Of Antioxidant Activity And Extraction Techniques For Commercially And Laboratory Prepared Extracts From Six Mushroom Species.
Sharpe, Erica; Farragher-Gnadt, Aiden P.; Igbanugo, Michael; Huber, Thomas; Michelotti, John C.; Milenkowic, Adam; Ludlam, Sylvia; Walker, Margaret; Hanes, Douglas; Bradley, Ryan; Bou-Abdallah, Fadi. 
Published Jun. 2021
Journal of Agriculture and Food Research

Cannabinol And Sleep: Separating Fact From Fiction. 
Corroon, Jamie. Cannabis and Published Oct. 2021
Cannabinoid Research 

Micronutrients For Attention-Deficit/Hyperactivity Disorder In Youths: A Placebo-Controlled Randomized Clinical Trial. 
Johnstone, J; Hatsu, I; Tost, G; Srikanth, P; Eiterman, L; Bruton, A; Ast, H; Robinette, L; Stern, M; Millington, E; Gracious, B; Hughes, A; Leung, B; Arnold, E. 
Published Jul. 2021
Journal of the American Academy of Child and Adolescent Psychiatry

Community Qigong For People With Multiple Sclerosis: A Pragmatic Feasibility Study. Buttolph, Lita; Corn, Joshua; Hanes, Douglas; Bradley, Ryan; Senders, Angela. 
Published Jun. 2021 
Journal of Alternative and Complementary Medicine

Protocol For The International Cohort On Lifestyle Determinants Of Health Study: A Longitudinal Investigation Of Complementary And Integrative Health Utilization In Postsecondary Education Students. 
Bradley, R; Pickworth, C; Wexler, R; Sadowski, A; Buttolph, L; Sarrar, H; Moehle, J; Torrens, MJ; Harnett, J; McIntyre, E; Schloss, J; Steel, A; Adams, J. 
Published Feb. 2021
Journal of Alternative and Complementary Medicine 

Symptoms Of Central Sensitization Are Associated With Worse Lower Urinary Tract Symptoms In Men.
Senders, A; Sajadi, K; Bauer, S; Le, T; Wexler, R; Chen, Y; Oken, B; Marshall, L. 
Published Sept. 2021
Journal of Urology

Lower Urinary Tract Symptoms Are Associated With Musculoskeletal Pain Among Older Men: Preliminary Evidence For Central Sensitization As A Mechanism. Senders, A; Bauer, S; Chen, Y; Oken, B; Fink, H; Lane, N; Sajadi, K; Marshall, L. 
Published Nov. 2021 
Neurourology and Urodynamics 

Phosphatidylserine For The Treatment Of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review And Meta-Analysis. 
Bruton, A; Nauman, J; Hanes, D; Gard, M; Senders, A. 
Published Apr. 2021
Journal of Alternative and Complementary Medicine  

Qualitative Analysis Of The Meals, Mindfulness, & Moving Forward (M3 ) Lifestyle Programme: Cultivating A ‘Safe Space’ To Start On A ‘New Path’ For Youth With Early Episode Psychosis.
Thompson, A; Senders, A; Seibel, C; Usher, C; Borgatti, A; Bodden, K; Calabrese, C; Hagen, K; David, J; Bourdette, D; Shinto, L. 
Published Feb. 2021
Early Intervention in Psychiatry 

Effects Of Different Allotments Of Avocados On The Nutritional Status Of Families: A Cluster Randomized Controlled Trial. 
Pacheco, Lorena S.; Bradley, Ryan D.; Denenberg, Julie O.; Anderson, Cheryl A. M.; Allison, Matthew A..  
Published Nov. 2021

Efficacy Of Herbal Treatments For Functional Dyspepsia: A Systematic Review And Meta‐Analysis Of Randomized Clinical Trials. 
Heiran, A; Bagheri Lankarani, K; Bradley, R; Simab, A; Pasalar, M. 
Published Dec. 2021
Phytotherapy Research 

A Naturopathic Treatment Approach For Mild And Moderate COVID-19: A Retrospective Chart Review.
Barber, M; Barrett, Richard; Bradley, R; Walker, E. 
Published Dec. 2021
Complementary Therapies in Medicine  

Mechanistic Support Of Traditional Persian Medicine For The Treatment Of Acne Vulgaris: A Scoping Review. 
Pasalar, M; Tabatabaei, F; Bradley, R; Tajadini, H; Kamali, M; Hasheminasab, F; Parvizi, M. 
Published Sept. 2021
Journal of Cosmetic Dermatology  

Efficacy Of Lettuce Seed Syrup On Insomnia In Patients With Breast Cancer: A Pilot Double Blind Randomized Placebo Controlled Clinical Trial.
Mosavat, Seyed Hamdollah; Mirzaei, Hamid Reza; Mofid, Bahram; Gharehgozlou, Reyhaneh; Parvizi, Mohammad Mahdi; Bradley, Ryan; Pasalar, Mehdi; Heydarirad, Ghazaleh. 
Published Aug. 2021
Journal of Complementary & Integrative Medicine 

Naturopathic Management Of Urinary Tract Infections: A Retrospective Chart Review. 
Garofalo, L; Zwickey, H; Bradley, R; Hanes, D.
Published Dec. 2021 
Journal of Alternative and Complementary Medicine 

Investigating Components Of Pranayama For Effects On Heart Rate Variability. Sharpe, E; Lacombe, A; Sadowski, A; Phipps, J; Heer, R; Rajurkar, SR; Hanes, D; Jindal, R; Bradley, R.
Published Sept. 2021
Journal of Psychosomatic Research 

Qualitative Impressions Of A Yoga Nidra Practice For Insomnia: An Exploratory Mixed-Methods Design. Sharpe, E; Tibbitts, D; Wolfe, B; Senders, A; Bradley, R.
Published Oct. 2021
Journal of Alternative and Complementary Medicine 

Potential Reversal Of Epigenetic Age Using A Diet And Lifestyle Intervention: A Pilot Randomized Clinical Trial. 
Fitzgerald, K; Hodges, R; Hanes, D; Stack, E; Cheishvili, D; Szyf, M; Henkel, J; Twedt, M; Giannopoulou, D; Herdell, J; Logan, S; Bradley, R. 
Published Apr. 2021

Predicting Non-Alcoholic Fatty Liver Disease For Adults Using Practical Clinical Measures: Evidence From The Multi-Ethnic Study Of Atherosclerosis. 
Rodriguez, L; Shiboski, S; Bradshaw, Patrick T.; Fernandez, P; Herrington, DA; Ding, J; Bradley, Ryan D.; Kanaya, A.
Published Sept. 2021
Journal of General Internal Medicine 

Characteristics Of Clients Seeking Yoga Therapy In A University-Based Student Clinic. 
Moonaz, Steffany; Sullivan, Marlysa; Nault, Daryl; Bright-Dumm, Irene; Bradley, Ryan. Published Jan. 2021
International Journal of Yoga Therapy

2019 Publications